Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS
Introduction: Malignant pleural mesothelioma (MPM) is a malignancy with a very poor prognosis for which new treatment options are urgently needed.We have previously shown that dendritic cell (DC) immunotherapy provides a clinically feasible treatment option.In the current study, we set out to assess the immunological changes induced by DC immunothe